Glioblastoma brain cancer (GBM) is the most dangerous and aggressive form of brain cancer.
GBM is classified as a grade IV astrocytoma.
GBM cells grow rapidly, with large number of cells reproducing at any given time. As a tumor grows, it leads to pressure on the brain, causing symptoms such as headaches, nausea, vomiting, and drowsiness.
GBM is challenging to treat because the cells within the tumor are very resistant to treatments. Doctors may try a variety of treatments to slow the growth of the tumor, but a cure and/or long term treatment options are still needed.
An estimated 14,000 + people will receive a GBM diagnosis in 2026.
GBM accounts for 50.1% of all primary malignant brain tumors.
The five-year survival rate for glioblastoma patients is only 6.9 percent, and the average length of survival for glioblastoma patients is estimated to be only 8 months.
Survival rates and mortality statistics for GBM have been virtually unchanged for decades.

Brain Cancer News

The Uncle Kory Foundation is a proud partner with The Mark Foundation to advance glioblastoma research and care. This coalition of philanthropies and brain cancer leaders are funding research aimed at overcoming the obstacles of brain cancer to effective diagnosis and treatment. The 2026 Awarded Research Projects can be found here.

From UCLA, Dr. Timothy D. Cloughesy; “New drug delays progression of glioma, a deadly brain cancer.”

From The Wall Street Journal, “Treatment Breakthrough for a Intractable Cancer.”

SurVaxM: Immunotherapy for Glioblastoma showing promise in clinical trials. Video: Experimental vaccine shows promise in delaying the return of aggressive brain tumor.